PhD in Computational Proteomics @ DKFZ

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Ihre Aufgaben:Your tasks

As a member of a newly founded computational biology group at DKFZ you will develop new statistical or computational methods to analyze high- throughput biological data with an emphasize on proteomics. The group works on quantitative analysis of genetic and physical interaction networks. Statistics and computational network analysis will be used to predict and understand interactions between genes, proteins and drugs in various ways with the aim to guide targeted drug therapies. The group will further develop methods that integrate available population level genetic data with experimental data. The candidate is expected to work in close collaboration with experimental scientists at DKFZ and other institutes in Heidelberg. Mass spectrometry is a powerful tool to quantify protein abundance and protein interactions. The successful candidate is expected to develop methods for the quantitative differential analysis of mass spectrometry data for protein abundance, post- translational modifications and protein interactions. You will develop robust statistical models for differential proteomics that are customized to the experimental circumstances. Recent developments in genome sequencing enable the sequencing for individual cancer tumors. In this project, you will utilize genome sequences in the proteomics analysis, both for identification and quantification of proteins. The proteins detected by the statistical analysis are characterized by machine learning methods and bioinformatics.

German Cancer Research Center-Deutsches Krebsforschungszentrum(DKFZ)

Ihr Profil:Your profile

  • The ideal candidate will have a master degree in a quantitative or computational science (statistics, computer science, bioinformatics, physics) with a strong background in applied statistics, machine learning or scientific computing. Programming skills in R are of advantage. The candidate should have interest in molecular or medical biology.

Wir bieten:We offer

  • Interesting , diverse workplace (Interessanten, vielseitigen Arbeitsplatz)
  • international Environment (Internationales Umfeld)
  • Compensation by TV –L (Vergütung nach TV-L)
  • Opportunities for part- time work (Möglichkeiten zur Teilzeitarbeit)
  • Flexible working hours (Flexible Arbeitszeiten)
  • Good education and training (Gute Fort- und Weiterbildung)

Online bewerben:apply online

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Read More

The candidate is expected to work in close collaboration with experimental scientists at DKFZ and other institutes in Heidelberg. Mass spectrometry is a powerful tool to quantify protein abundance and protein interactions.