SAN DIEGO and PARIS, June 7, 2013 /PRNewswire/ -- BioNano Genomics
announced today the availability in the European Union of the Irys™
System for genome mapping. In conjunction with the European Human
Genetics Conference 2013 being held in Paris from June 8 to 11, BioNano and collaborator Pui-Yan Kwok, M.D., Ph.D., Henry Bachrach Distinguished Professor at the University of California, San Francisco
(UCSF), will present the first demonstration of a de novo map of the
human genome using the Irys System and the utility of this map in the
analysis of structural variation and genome finishing.
"We are excited to expand the global market for Irys, so cutting edge labs in Europe and beyond can access the power of long-read technologies to drive genomic discoveries," said Erik Holmlin,
Ph.D., president and CEO of BioNano Genomics. "De novo physical maps
are proving to be crucial for fully characterizing genomes. We are
thrilled to demonstrate today that the Irys platform can scale to
larger, more complex genomes, such as human. This achievement paves the
way for the launch of human genome capabilities, which will include a
new high-throughput IrysChip, to be announced in the second half of this
year."
Dr. Holmlin continued, "With the Irys System's nanochannel
array technology, we are able to deliver the long-range genomic
information genomics researchers and clinicians need for the accurate
detection of genomic structural variation and to finish genome
assemblies. Irys has significant applications throughout human genomics
and epigenomics and will be especially useful in biomedical disease
research and to ultimately empower diagnostics."
BioNano Genomics
will be at Booth 692 at the European Human Genetics Conference 2013
presented by the European Society of Human Genetics (ESHG). In addition,
Dr. Kwok, will be giving a podium presentation at the conference.
Details of the presentation are as follows:
Title:
|
C01.4
- Mapping of two human genomes with a single molecule nanochannel array
platform for genome-wide structural variation analysis and de novo
sequence assembly
|
Session:
|
C01. Structural variation and de novo mutations.
|
Date/Time:
|
6/9/2013 1:15 PM - 2:45 PM
|
Room:
|
Grand Amphitheatre
|
About Irys
Irys makes it
possible to routinely and accurately detect genomic structural
variation and to finish genome assemblies. The fully automated Irys
benchtop instrument uses the IrysChip to uncoil and confine long DNA
molecules in proprietary Nanochannel Arrays™ where they are uniformly
linearized in a highly parallel display for high-resolution,
single-molecule imaging. Irys does not employ DNA fragmentation or
amplification, which are typical with next-generation sequencing. The
result is sequence information over extremely long "reads" ranging from
hundreds of kilobases to a megabase, where the sample's valuable
structural information is preserved. Irys makes it possible for
researchers to directly observe structural variants including
replications, deletions, translocations and inversions.
About BioNano Genomics
Headquartered in San Diego,
BioNano Genomics is delivering an altogether better way of gaining a
fully informed understanding of genomes. The Company's platform provides
researchers and clinicians the most comprehensive, organized and
actionable picture of a genome with unprecedented insights into how the
individual components of genomes are ordered, arranged, and interact
with each other. BioNano Genomics works with institutions in life
science, translational research, molecular diagnostics and personalized
medicine. The Company is supported by private investors and grant
funding from genomics programs at federal agencies, including the NIH
and NIST-ATP.
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