The GenoCon rational genome design platform uses open data technology to create and share designs with the world, utilizing professional laboratories to synthesize and test designs under protected conditions.
Open design, in synergy with closed synthesis and experimentation, harnessing crowd innovation safely.
GenoCon is an international open rational design platform for genome construction that utilizes an Open Data Innovation (ODI) philosophy for Synthetic Biology to harness crowd innovation to support life-science technology research.
GenoCon challenges participants to design synthetic DNA sequences on the computer, as solutions to cutting-edge problem assignments. Participants make use of semantically linked data from scientific databases and literature to construct their solutions. Though the challenge problems are advanced scientific research areas, software tools (a CAD environment) are provided so as to make the challenge accessible to nonspecialist researchers and even students. Submitted DNA designs are selected for quality and originality.
Currently, the GenoCon2 biannual international competition focuses on modifying the genome of the thale cress plant Arabidopsis thaliana. The reward for a good design: GenoCon pays for the synthesis of the DNA and its transformation into a real plant!
A GenoCon laboratory then characterizes the transgenic plant with state of the art quantitative measurement equipment and data analysis methods. The GenoCon committee then reviews the results and scores each design for performance. Winning design contestants will be invited to contribute to publication of GenoCon results, in addition to contest prizes.
The New GenoCon2 Challenge Assignment: Design synthetic plant promoters to control gene expression – tissue and/or time specific!
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