Bioinformatics Algorithms reveal Genomic Inconsistency in STAP Study

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“The scientific process requires replicating and extending existing data,” said George Q. Daley, HMS professor of biological chemistry and molecular pharmacology at Boston Children’s and co-senior author on both papers addressing the STAP controversy.
  • Tremendous controversy erupted in early 2014 when two papers published inNature described how a technique called “stimulus-triggered acquisition of pluripotency,” or STAP, could quickly and efficiently turn ordinary cells into pluripotent stem cells, that is, stem cells capable of developing into all the tissues in the body.
  • The simplicity of the approach — subjecting the cells to particular stresses like mild acid exposure — seemed too good to be true. And it was.

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