Two PhD positions are available for outstanding and enthusiastic students with an interest in Developmental Genetics and Vascular Biology. These positions are available in the Hogan laboratory at the Institute for Molecular Bioscience (http://www.imb.uq.edu.au/ben-hogan) and will involve the in vivo analysis of vascular development, vascular cell biology and molecular mechanisms of angiogenesis/lymphangiogenesis using zebrafish and mouse embryos as model systems.
Welcome to UQ
IMB is equipped with state-of-the-art research infrastructure including mouse and zebrafish facilities, advanced imaging and genomics platforms, high-throughput sequencing, advanced bioinformatics and proteomics – all of which support the Institute's leading life sciences research. Details of the research interests of the Institute may be accessed on the Institute's website at: http://www.imb.uq.edu.au
The role
- We are seeking dynamic, intelligent, highly motivated PhD students to work on two distinct projects. These projects will be designed in full with the successful applicants input but will span the following major focus areas in the laboratory:
- Gene discovery through novel zebrafish mutants. We recently completed a forward genetic screen atIMB/UQ for mutants with defects in vein and lymphatic vessel development. This screen was coupled with whole genome sequence mutant mapping and we identified several new genes. Phenotypes will be examined with cellular resolution, molecular mechanisms of gene function will be analysed and conservation will be examined using zebrafish and mouse models. The goal is to identify novel pathways and mechanisms in vascular development.
- Improving the dynamic visualisation of vascular development. The project will develop novel transgenic resources using traditional as well as genome editing approaches (CRISPR) to visualise cellular lineages in vascular development and sub-cellular processes that contribute to vascular development. The goal is to expand our capabilities and the resolution of analysis possible in vivo during embryonic vascular development.
The Candidate
- Both Australian and international applicants are welcome to apply. Candidates should have a First Class Honours degree (or equivalent) in genetics, developmental biology, cell biology, molecular biology or a related discipline. Strong academic performance, the commitment to conduct high quality biological research, and published output will be additional assessment criteria.
Applicants must be eligible to enrol in a PhD with the University of Queensland. For a complete list of the University of Queensland's minimum entry requirements please refer to: http://www.uq.edu.au/grad-school/our-research-degrees.
Scholarship and Remuneration
- Appointment to the position is contingent upon receipt of an APA or IPRS scholarship through one of UQ's scholarship rounds.
- Prospective students will be provided with assistance to apply for either the Australian Postgraduate Award (APA) or, for international students, an International Postgraduate Research Scholarship (IPRS). The current scholarship rate for the APA is AUD$25,392 per annum (2014 rate, indexed annually) tax-free for three years with the possibility of a six month extension in approved circumstances.
- For further information on scholarships please refer to http://www.uq.edu.au/grad-school/scholarships-and-fees.
Enquiries
| Dr Ben Hogan Co-Division Head, Genomics of Development and Disease Division P: +61 7 3346 2105 E: [email protected] |