GenomeDx Biosciences is a dynamic entrepreneurial startup molecular diagnostics company focused on cancer genomics. Whether on the phone with patients, or in the cloud with big data, our innovators are working hard to give back to the patient what cancer takes away: information for life.
Our team is constantly learning from each other, from patients and from urologic oncology professionals in world-renowned cancer institutions. We work in multi-disciplinary, collaborative project teams that enable us to respond effectively to an evolving, growing, data-driven environment. The company is currently seeking a motivated Bioinformatician with a strong cancer biology and computational biology skill set to help develop Decipher GRID. This individual will work in a multidisciplinary team of researchers and will be responsible for developing GRID content.
GenomeDx Information for Life
The Decipher GRID™ (Genomic Resource Information Database),is aimed at providing personalized genomic information to patients suffering from urologic cancers. This genomic database is the largest transcriptome-wide, clinically annotated urologic cancer database in the world and is being leverage by top researchers worldwide to better understand molecular drivers of prostate and bladder cancer. GenomeDx is developing tools to utilize GRID to assign patients to clinical trials based on the patient’s tumor genomics.
If you think you have what it takes to be part of an elite group of entrepreneurial innovators we invite you to consider joining the GenomeDx team.
Roles & Responsibilities:
Datamine relevant information from clinical trials, drug-target databases, and other databases
Develop rigorous computational methods to infer functional activity of genes, biological processes and druggable pathways
Optimize biologically and clinically relevant expression cut-points
Port and optimize crowd-sourced genomic signatures to the Decipher platform
Develop algorithms to prioritize drug candidates for patients based on tumor genomics
Work with large genomic datasets to develop and test new algorithms and hypothesis
Use biological networks and systems biology to better understand prostate cancer progression and potential treatment effects
Infer underlying cancer development mechanisms from empirical observations
Search literature and be on the top of studies related to prostate and bladder cancer prognosis and treatment
Explore genomic knowledge of other cancers (i.e breast, colon) in prostate and bladder cancer
Communicate findings to colleagues, collaborators, and key opinion leaders through presentations and academic publications
Qualifications
PhD in Cancer Molecular Biology, Cancer Genomics, Bioinformatics, or related field
Experience analyzing expression microarray data
Working knowledge of cancer genomics, bioinformatics, and computational biology
A deep understanding of cancer therapeutics and their impact on tumor genomics
Excellent written and spoken communication
Strong academic publishing record
Experience working with urologic cancers a plus
Benefits
Competitive Salary with medical and dental benefits
Access to large clinically relevant, transcriptome-wide cancer datasets
Opportunities to collaborate and learn from world leading prostate and bladder cancer researchers from Mayo Clinic, John Hokpins Medical Institute, MD Anderson, and many others
Access to powerful computers for massively parallel, big-data number crunching
Opportunities may also include attending conferences and continued education
The Decipher GRID™ (Genomic Resource Information Database),is aimed at providing personalized genomic information to patients suffering from urologic cancers. This genomic database is the largest transcriptome-wide, clinically annotated urologic cancer database in the world and is being leverage by top researchers worldwide to better understand molecular drivers of prostate and bladder cancer. GenomeDx is developing tools to utilize GRID to assign patients to clinical trials based on the patient’s tumor genomics.
