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The Department of Medicine at Weill Cornell Medical College is seeking a highly motivated researcher with a computational biology/bioinformatics background to join our team. We are seeking a dynamic individual who will be responsible, as a member of a team, for providing computational support for a range of activities. Expertise will be applied to answer key biological questions exploring molecular abnormalities, which contribute to the pathogenesis of Myeloid Disorders (including, but not limited to, Acute Myeloid Leukemia and Myeloproliferative Neoplasms).

Research Leads to Cures Initiative: Weill Cornell Medical College

  • The candidate is expected to execute integrative analyses of large datasets generated from clinical and functional genomic data from in-house experiments and/or available public repositories, by developing and applying computational pipelines mainly focused on next generation sequencing data and other large-scale datasets. The work will be performed under the supervision of faculty members (Dr. Francine Garrett-Bakelman, Dr. Christopher Mason and Dr. Ari Melnick) and with staff in the Division of Hematology and Medical Oncology and Cancer Center. The applicant would join a thriving and highly interactive research team including cancer biologists, hematopathologists, and computational biologists.

Applicants with the following qualifications and expertise:

  • Training in a bioinformatics, computer science, biostatistics or related field (masters or higher degree), together with a background in molecular biology or a related field.
  • A minimum of two years experience in analysis of next generation sequencing data, familiarity with graphics/visualization software for genomics and an understanding of the principals and use of biostatistics as applied to molecular level data.
  • Experience with large-scale computational and statistical analyses.
  • Experience in analysis of microarray data as well as integrative analysis approaches
  • Experience with using computational and statistical tools (for example: bwa, samtools, Picard, GATK, bedtools, R, etc.)
  • Experience with Unix/Linux computing environment, data management and organization, and general programming
  • knowledge and ability to automate tasks using scripting languages such as bash, perl, python, R, or Java.
  • Experience with large-scale computational cluster job submissions (SGE or PBS) for high-throughput data analysis.
  • Experience with several of the following activities is desirable: proteomic analysis, phylogenetic analysis, comparative genomics, SNP and CNV analysis, trancriptomic and epigenomics data analysis and an understanding of emerging and commonly used bioinformatics tools.
There will be opportunities for training to complement current skills, and we envision numerous collaborations with other outstanding computational scientists at the Institute for Computational Biomedicine. Hence, good relational and communication skills are highly desirable.
  • Appointments are for one year, with renewal based upon satisfactory performance and funding availability.
  • Please send cover letter, one select publication and resume, including names of three references, to:
Attn: Francine Garrett-Bakelman, MD, PhD
E-MAIL:
[email protected]

Inside Medicine - Solving Sarah's Puzzle

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The Leibniz Research Cluster (LRC) Bio/Synthetic multifunctional micro-production units – Novel ways in compound development is a joint research programme of five Leibniz Institutes and combines life sciences and engineering to develop novel processes for cell free production of natural products. At the Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute Jena (HKI,www.leibniz-hki.de) we recently established the LRC Junior Research Group “Biobricks of microbial natural product syntheses”. The group is funded by the German Ministry of Education and Research in the framework of the initiative “Biotechnology 2020+” for up to five years.

Joint Research at the Hans Knöll Institute

2 PhD positions for three years initially in the field of Synthetic Microbiology

  • The successful candidates will be involved in the genomic manipulation of model organisms to heterologously express eukaryotic secondary metabolite gene clusters.

Our requirements

  • We expect a Master’s degree (or equivalent) in Life Sciences (e.g. Biology, Microbiology, Biochemistry) with a strong background in molecular biological techniques. Experience in microbiology is advantageous but not required. Applicants should have very good communication skills in English and a high motivation to perform team-oriented as well as independent work.

The field of work

  • includes the genomic manipulation of model organisms (e.g. Saccharomyces cerevisiae and Aspergilli); the identification and isolation of active metabolites; the elucidation of metabolic pathways and their key elements (e.g. polyketide synthases). The project aims to optimize the expression of cryptic gene clusters and to identify new therapeutics.

We offer

  • The successful candidates will be hosted in the independent LRC Junior Research Group “Biobricks of microbial natural product syntheses” headed by Dr. Vito Valiante. The HKI is embedded in the outstanding scientific environment of the Beutenberg Campus providing state-of-art research facilities and a highly integrative network of life science groups. We offer a multifaceted scientific project supported by excellent technical facilities, a place in a young, committed team, as well as strong scientific collaborations. As a PhD student, you will be integrated in one of the established graduate schools ILRS (www.ilrs.de) or JSMC (www.jsmc.uni-jena.de), which offer extensive mentoring support and provide additional training through a structured onsite programme. Training will include key areas of science and technology, and complementary skills.
  • Salary is paid according to German TV-L (salary agreement for public service employees). The HKI is an equal opportunity employer.
Further information: Dr. Vito Valiante | +49 3641 532 1090 | [email protected]
  • Complete applications in English should include a CV, a complete list of publications, a brief statement of research experiences and interests, the addresses of two possible referees, and should be submitted until May 31, 2015 referring to HKI job posting No. 10/2015 to [email protected]. The HKI is committed to increase the percentage of female scientists and therefore especially encourages them to apply.

Mail address:

Leibniz Institute for Natural Product Research and Infection Biology
– Hans Knöll Institute –
Personnel office
Adolf-Reichwein-Straße 23
07745 Jena | Germany

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J. Craig Venter

Craig Venter, Ph.D., is regarded as one of the leading scientists of the 21st century for his numerous invaluable contributions to genomic research. He is founder, chairman, and CEO of the J. Craig Venter Institute (JCVI), a not-for-profit, research organization with approximately 250 scientists and staff dedicated to human, microbial, plant, synthetic and environmental genomic research, and the exploration of social and ethical issues in genomics.

Artificial Intelligence helps mold future of genomics


J. Craig Venter Institute CEO J. Craig Venter discusses human longevity and where science is taking us.Watch Maria Bartiromo talk about Strategy on Opening Bell.

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A doctoral position is an available doctoral education project to which a PhD student is to be recruited. After the selection process the process for admission to doctoral education will commence. An admission decision will not be taken until an individual study plan has been approved by the departmental admission board.For more information regarding doctoral (PhD) education, see: http://www.ki.se/doctoral.

Studying at Karolinska Institutet

Description of research group and project

  • The research group of Carsten Daub at the Department of Biosciences and Nutrition aims at understanding the changes of transcriptional regulation connected to diseases, either as consequence or as cause for the disease. For this, we are working together with several research groups in the medical and clinical field at Karolinska Institutet and Karolinska Hospital as well as with other research groups and consortia around the world.
  • We profile the expression of coding and non-coding transcripts using RNASeq, Cap Analysis Gene Expression (CAGE) and small RNA-Seq. Employing state-of-the-art computational methods we infer likely underlying gene regulatory events. By intensively discussing with our collaborators we take full advantage of the usually rich body of knowledge available for the studied disease or process together with complementary phenotypic sample characteristics. Through this, and together with our collaborators, we are as a team able to identify a core set of targets for in-depth functional validation. The Daub lab is co-affiliated with the Science for Life Laboratory (SciLifeLab), Sweden’s largest high-throughput sequencing and proteomics facility.
The position offered here is part of a European Union Marie Sklodowska Curie Initial Training Network named “ZENCODE-ITN” (http://www.birmingham.ac.uk/zencode-itn). The scientific focus of the consortium is to understand genome regulation through combined experimental and computational approaches in the model vertebrate zebrafish. The consortium aims at training young scientists in both computational biology and experimental wet lab biology. The consortium comprehensively annotates functional epigenetic and transcribed elements, decipher genomic codes of transcription, as well as coding and noncoding gene function during vertebrate development and enhance zebrafish as an attractive developmental, comparative genomic and disease model. The appointed fellow will immensely benefit from other training network participants, which include major zebrafish genomics laboratories, eminent computational biologists and world-class genomics technology experts.

Duties

  • The consortium will produce a variety of complementary genome-wide data including ChIP-Seq, CAGE, miniCAGE, and RNA-Seq. The PhD student will first develop data structures that are the basis for sharing heterogeneous data across the consortium as well as for data dissemination with the publication. The student will consolidate consortium data and develop annotation strategies together with the consortium members. Importantly, the student will creatively develop and implement data visualization methods for the consortium data including primary data and analysis results. The student will also be involved in data analysis of consortium data related to specific biological questions.

Qualifications

The PhD program at Karolinska Institutet corresponds to 4 years full time studies. We are seeking a highly motivated and talented PhD student who creatively plans, thoroughly executes and interprets data structures, annotation and visualization of heterogeneous high-throughput sequencing data. As successful candidate you have a masters degree in Bioinformatics, computer science, computational biology or a related field. Systematic thinking and excellent programming skills are essential. Experience with analysis of high-throughput data and experience with sequencing data is a strong plus. Excellent communication skills, a proactive and constructive personality as well as fluent English speaking and writing abilities are expected.
  • The position is funded by a European Union Marie Sklodowska Curie Initial Training Network (ITN). Therefore, potential candidates must not have resided or carried out their main activity (work, studies, etc.) in Sweden for more than 12 months in the 3 years immediately prior to the recruitment, and have no more than 4 years of research experience since the degree that would qualify for admission onto the PhD programme, e.g. Masters degree.

Entry requirements for doctoral education at KI

To be eligible for doctoral education following requirements has to be met:

General entry requirements A person meets the general entry requirements for doctoral/third-cycle/PhD education (according to Higher Education Ordinance Chapt 7, section 39) if he/she:
  1. has been awarded advanced/second-cycle/master qualification (i.e. master degree) or
  2. has satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second-cycle/master level, or
  3. has acquired substantially equivalent knowledge in some other way in Sweden or abroad.

Specific entry requirements

  • Proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school:
  • Proficiency in the English language can be documented by an internationally recognized test such as TOEFL or IELTS, see web-link below for more information.
  • Applicants who meet the general entry requirements (1 or 2 above) from a university in one of the Nordic countries fulfill the requirements in English.
  • For more information regarding general and specific entry requirements: http://ki.se/en/education/entry-requirements-eligibility-for-doctoral-education

Assessment criteria

A selection will be made among qualified applicants on the basis of the ability to benefit from doctoral education. Karolinska Institutet uses the following bases of assessment:
  • Documented subject knowledge of relevance to the area of research
  • Analytical skill
  • Other documented knowledge or experience that may be relevant to doctoral studies in the subject

The qualifications of the applicants will be evaluated on an overall basis.

Terms and conditions

  • The most common way of financial support for doctoral students at KI is doctoral grant the first year and a doctoral studentship (doctoral employment) for year 2, 3 and 4. During the time between recruitment and admission a short-term employment can be offered for up to 6 months.

Application process

An application must contain the following documents in English:

  • A personal letter and curriculum vitae
  • A copy of degree certificates and associated certificates
  • A copy of degree projects and any previous publications

The application is to be submitted through the MyNetwork recruitment system.

Apply Online

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These Awards will honor four scientists, whose outstanding research in the life sciences is contributing to progress in global health, specifically in the following fields:
  1. TROPICAL AND NEGLECTED DISEASES
  2. NEURODEGENERATIVE DISEASES AND AGEING
  3. DRUG RESISTANCE
  4. IMMUNOLOGY

Sanofi Institut Pasteur Awards 2014 - Meet Dr Etienne

Sanofi Institut Pasteur Awards 2014 - Meet Dr Priscille Brodin

Sanofi Institut Pasteur Awards 2014 - Meet Dr Nadine

Sanofi Institut Pasteur Awards 2014 - Meet Dr Jean-Laurent Casanova

There will be three categories of awards:

  1. One International Senior award (€ 125 000)
  2. One International Mid-career award (€ 75 000) 1
  3. Two National Junior awards (€ 50 000 each) 2
Deadline to submit nominations:Tuesday, 28th April, 2015
Contact: [email protected]

Submit Application

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PhD fellowship in Micro- and Nanofabrication for Neurobiology

Medical technology, nanomedicine, bionanotechnology, and biotechnology are strategic areas within NTNU. By coupling nanotechnology/microsystems directly with biomedicine and biotechnology, novel approaches for discovery, diagnosis and therapy are expected to emerge.
The PhD position is for 3.5 years including a total of 30 credits from NTNU's PhD courses. For regulations concerning the PhD-degree at NTNU, please see:
http://www.ntnu.edu/dmf/research/phd
  • The PhD position is part of start-up projects in designing, making and testing of microfluidic devices and electrophysiological reading of designer neuronal cell networks, neurons-on-a-chip. More specifically the PhD student will design and fabricate in PDMS microchannels and/or biofunctionalized gold-on-glass patterns to study cellular assemblies, neuron-bundle function and axonal outgrowth to enable creation of functional neuronal cell circuits and study neuronal plasticity. At later stages it is expected that these designer neuronal cell networks will be monitored on microelectrode arrays (MEAs).

Winter in Trondheim 2014, by Natural Light

The successful applicant is expected to work independently in the cleanroom and with biological testing of devices in close collaboration and communication with biomedical research environments. Furthermore, the candidate is expected to have a 6-12 month research stay at a collaborating laboratory abroad. The applicant must start in the position at the latest September 2015. A strong background in microfabrication for life science is recommended. Candidates with a strong background in microsystems for neurobiology will be preferred.

For this position the applicants must have:

  • a master’s degree or equivalent education, submitted no later than May 2015. The academic record must have a weighted average grade of B or higher, in accordance with NTNU’s grading system.
  • training with relevance to this project
  • experience in microfabrication, microsystems, or nanotechnology for life sciences, ideally with experience with microfluidics, mammalian cell biology (neurobiology), cell culture, electrophysiology and microscopy

Emphasis will also be placed on

  • the candidates’ motivation for the position
  • documented ability to work independently and as a team player
  • the ability to communicate and give oral and written presentations in English
  • A successful applicant is highly competent, flexible and an ambitious person
    Candidates from universities outside Norway are kindly requested to send a Diploma Supplement or a similar document, which describes in detail the study and grade system and the rights for further studies associated with the obtained degree: http://ec.europa.eu/education/policies/rec_qual/recognition/diploma_en.html
  • A good work environment is characterized by diversity. We encourage qualified candidates to apply, regardless of their gender, functional capacity or cultural background. If necessary, we will adapt the workplace for people with disabilities. Increasing the number of women in academic positions is an important priority for the Norwegian University of Science and Technology.
  • Depending on qualifications and academic background, PhD candidates at the Faculty of Medicine will be remunerated at wage levels 50-58 on the Norwegian State salary scale, with gross salary from NOK 429 400 – NOK 491 100a year, of which 2 % is deducted for the Norwegian Public Service Pension Fund. A yearly amount for operating costs will be added. The appointment will be made in accordance with current regulations and supplementary rules with guidelines for employment as PhD candidate appointments at universities and university colleges.

How to apply:

The allocated means are intended for new fellowships. Candidates who hold, or have already held a PhD position at NTNU cannot be rehired at NTNU in the same type of position.
The candidate must be fluent in both spoken and written English. Candidates from non-English speaking countries outside the Nordic countries must provide official documentation of their English competence. Approved tests are TOEFL, IELTS and Cambridge Certificate in Advanced English (CAE) or Cambridge Certificate of Proficiency in English (CPE). The following results are required: TOEFL: 600 / writing 4.5 (paper-based test), 92 / writing 22 (internet- based test) IELTS: 6.5, with no section lower than 5.5 (only Academic IELTS test accepted) CAE/CPE: grade B or A.

The candidate’s motivation, skills and personal qualifications for the position and project should be described in the application letter. The application should contain the following attachments:

  • Applicants’ CV (including list of publications, relevant former positions and copy of relevant transcripts and diplomas)
  • Short statement from a former supervisor/tutor/teacher
  • Contact information for two references (including email addresses and telephone number)
  • Other relevant information
  • Deadline for applications: April 30th 2015
  • For further information about the position, please contact Professor, Øyvind Halaas, Department of Cancer Research and Molecular Medicine. Phone (+47) 977 90 870, [email protected]
  • For information concerning the application process, please contact: HR-consultant Mariann Hansen (+47) 482 80 634, [email protected].

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The Vader lab at the Max Planck Institute of Molecular Physiology in Dortmund, Germany invites applications for a three-year, ERC-funded PhD position. We use the budding yeast Saccharomyces cerevisiae to study how cells maintain genomic stability during meiosis, the specialized cell division that is essential for sexual reproduction. We are broadly interested in understanding how organisms manage the processes of DNA break formation and repair during meiosis. To study this, we use genome-wide analysis of DNA break formation coupled with genetics, molecular cell biology and biochemistry.

  • The successful candidate must have obtained a MSc degree in biology, molecular life sciences or a related field. Previous experience in yeast genetics, next-generation sequencing, bioinformatics or cell biology is considered a plus. Candidates are expected to become part of the International Max Planck Research School in Chemical and Molecular Biology (http://www.imprs-cmb.mpg.de)

For more specific information on research projects and themes please visit:http://gerbenvader.wix.com/meiosis, or http://www.mpi-dortmund.mpg.de/48579/fg_vader

  • Applications (written in English) should be directed to: [email protected] and include
  • A cover letter discussing your research interests and future plans
  • A curriculum vitae
  • Two letters of recommendation

MARI themes

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