2015 is a special year for the Helmholtz Centre for Infection Research (HZI) in Braunschweig:turning 50! In October 1965 the first laboratories took up work on the campus were the HZI is now located.
Since the beginnings a lot has changed. Founded as the Institute of Molecular Biology, Biochemistry and Biophysics (IMB), the Federal Republic of Germany became the main stakeholder of the institute in 1975 which was then renamed as German Research Centre for Biotechnology mbH (GBF) in 1976. Since then the GBF was a member of the Association of National Research Centers (AGF), which later became the Helmholtz Association. From the early 2000s a shift in the research focus of the Centre started taking place resulting in the Centre being renamed Helmholtz Centre for Infection Research in 2006.
HZI International Graduate School
open vacancies @ Helmholtz Centre for Infection Research
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PhD Position in CRISPR-Cas9 biology and genome engineering
Extended application period - The department Regulation in Infection Biology (Prof. Emmanuelle Charpentier) at the Helmholtz Centre for Infection Research in Braunschweig (Germany) is offering a PhD Position to investigate the biochemical mechanism of RNA-mediated CRISPR-Cas9 and further develop the system for targeted genome engineering in human cells. See recent key publications in 2011 (Nature 471:602-607), 2012 (Science 337:816-821) and 2014 (Science 346:1258096).
Area of research
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The Helmholtz department “Regulation in Infection Biology” studies molecular and cellular mechanisms of regulation in processes of
infection and immunity in Gram-positive bacterial
pathogens. The group has recently focused on the
RNA-programmable CRISPR-Cas9 endonuclease and is currently investigating the biochemistry of the system and its applications in genome editing and regenerative medicine. The project will be conducted in cooperation with the biotech company CRISPR Therapeutics.
Prerequisite
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Master’s Degree/Diploma in Biology, Biochemistry, Bioinformatics, Biotechnology, Life Sciences, Microbiology, Immunology or related fields.
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Former experience in molecular biology, biochemistry, genetics, cell biology and genome editing will be considered as an advantage.
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Ability to work independently and as part of international and multidisciplinary consortia.
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Ability to multi-task and to meet tight deadlines is essential.
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Ability to work in a highly competitive field of research.
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A strong desire to do research with high self-motivation and enthusiasm.
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Excellent organization skills and personal initiative.
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Excellent English communication skills (written and spoken).
Location
Research Group
The Handicapped
- Qualified applicants with a disability will be given preference.
How To Apply
Applications accepted until 18.02.2015
The application period for this position has been extended. Please submit your application in online application tool at https://hzi.opencampus.net/ (after registration choose “Application HZI Jobs” and select job number 84/2014).
Within the online application, you have to provide a complete curriculum vitae including a list of publications and academic references, as well as a motivation letter outlining briefly your research experience, motivation in the position and own scientific interests within the context of the announced research topic. All documents and information should be provided in English.
PhD Position in infection biology and innate immunity
Extended application period - The department Regulation in Infection Biology (Prof. Emmanuelle Charpentier) at the Helmholtz Centre for Infection Research in Braunschweig (Germany) is offering a PhD Position to investigate mechanisms of interaction between Streptococcus pyogenes and the human host.
Area of research
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The Helmholtz department “Regulation in Infection Biology” studies molecular and cellular mechanisms of regulation in processes of
infection and immunity in Gram-positive bacterial
pathogens. The group has recently focused on the mechanisms of interaction between Streptococcus pyogenes and innate immune cells. In this regard, the project will involve the investigation of mechanisms involved in the recognition of the bacterial pathogen by human
host cells and will include the study of membrane vesicles in this respect. The position is announced within the frame of a recently funded European ERA-NET project, Infect-ERA Haplo-Infect.
Prerequisite
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Master’s Degree/Diploma in Biology, Biochemistry, Bioinformatics, Biotechnology, Life Sciences, Microbiology, Immunology or related fields.
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Former experience in immunology, molecular biology, biochemistry, bacteriology and genetics will be considered as an advantage.
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Ability to work independently and as part of international and multidisciplinary consortia.
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Ability to multi-task and to meet tight deadlines is essential.
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Ability to work in a highly competitive field of research.
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A strong desire to do research with high self-motivation and enthusiasm.
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Excellent organization skills and personal initiative.
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Excellent English communication skills (written and spoken).
Location
Research Group
The Handicapped
How To Apply
Applications accepted until 18.02.2015
The application period for this position has been extended. Please submit your application in online application tool at https://hzi.opencampus.net/ (after registration choose “Application HZI Jobs” and select job number 85/2014).
Within the online application, you have to provide a complete curriculum vitae including a list of publications and academic references, as well as a motivation letter outlining briefly your research experience, motivation in the position and own scientific interests within the context of the announced research topic. All documents and information should be provided in English.
PhD Position in Clp-mediated regulatory proteolysis in bacteria
Extended application period - The department Regulation in Infection Biology (Prof. Emmanuelle Charpentier) at the Helmholtz Centre for Infection Research in Braunschweig (Germany) is offering a PhD Position to investigate regulatory mechanisms of Clp-mediated protein quality control including proteolysis in Gram-positive bacterial pathogens.
Area of research
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The Helmholtz department “Regulation in Infection Biology” studies molecular and cellular mechanisms of regulation in processes of
infection and immunity in Gram-positive bacterial
pathogens. The group has recently focused on mechanisms involving Clp-mediated
protein quality control, toxin-antitoxins systems and
RNAregulatory elements.
Prerequisite
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Master’s Degree/Diploma in Biology, Biochemistry, Bioinformatics, Biotechnology, Life Sciences, Microbiology, Immunology or related fields.
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Former experience in
protein biochemistry, bacteriology, molecular biology and genetics will be considered as an advantage.
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Ability to work independently and as part of international and multidisciplinary consortia.
-
Ability to multi-task and to meet tight deadlines is essential.
-
Ability to work in a highly competitive field of research.
-
A strong desire to do research with high self-motivation and enthusiasm.
-
Excellent organization skills and personal initiative.
-
Excellent English communication skills (written and spoken).
Location
Research Group
The Handicapped
How To Apply
Applications accepted until 18.02.2015
The application period for this position has been extended. Please submit your application in online application tool at https://hzi.opencampus.net/ (after registration choose “Application HZI Jobs” and select job number 86/2014).
Within the online application, you have to provide a complete curriculum vitae including a list of publications and academic references, as well as a motivation letter outlining briefly your research experience, motivation in the position and own scientific interests within the context of the announced research topic. All documents and information should be provided in English.
contact
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You are encouraged to contact directly the Department Head. For questions regarding offered PhD projects, please contact
Prof. Charpentier under: [email protected].
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The Helmholtz Centre for Infection Research (HZI) is a member of the Helmholtz Association of German Research Centres, the largest scientific organization in Germany. The HZI offers a unique research environment in the field of
infectionbiology, excellent state-of-the-art equipment, a stimulating scientific community and intensive training of scientific and personal skills. Further information about the institute and the research department of Prof. Charpentier can be found on website:
www.helmholtz-hzi.de.
Online Application of the HZI Graduate School
Read More
http://www.helmholtz-hzi.de/en/career/jobs/phd_theses
