Job title:Interdisciplinary PhD in Systems Biology, Bioinformatics, and Immunology (SIB - group M. Delorenzi, CHUV group D. Zehn)We consider applications for an interdisciplinary PhD in the area of systems biology and bridging bioinformatics, transcriptional networks identification and molecular regulation of immune responses during acute and chronic infections.
Specifically the projects involves:
- Analysis of molecular data (mRNA and or NGS)
- Building co-expression networks, identification of hub genes, and key transcription factors
- In vivo validation of identified candidate genes
Welcome to the University of Lausanne
| Start date | Open |
| Employment fraction | Open |
| City | Lausanne |
| Application deadline | mid December 2014 (earlier=better) |
| Job reference | BCF-JobAd-Sept2014-PHDimm |
| Initial Duration | Open |
The project will be performed in close collaboration between the bio-informatics laboratory of M. Delorenzi and the immunology oriented laboratory of D. Zehn. The project aims to unravel and verify the molecular mechanisms underlying T cell dysfunction in chronic infections and the failure of the immune systems to clear certain pathogens. Comprehensive training in bio-informatics analysis will be provided and sophisticated state of the art techniques will be used to in vivo investigate the function of candidate molecules in immune effector cells in models of infection. Candidates will join the PhD program “Cancer and Immunology” of the University of Lausanne and the SIB PHD training network (http://www.isb-sib.ch/training/sib-phd-training-network.html).
Profile requirements
- Enthusiastic interest for trans-disciplinary research (medicine, molecular biology, genomics, computing-programming, statistics)
- Good knowledge and proven skills in one or more of these fields.
- Good English speaking and writing skills.
Additional skills of interest
- Knowledge in molecular biology and / or immunology
- Skills in biostatistics / data analysis methods
- Experience in the use of R software.
- Experience in software development.Salary & Benefits
Additional information
- SIB is a not-for-profit organization that offers excellent bioinformatics infrastructure.
- The CHUV is the hospital of the University of Lausanne.
- Lausanne offers a very stimulating environment with many research institutions and a
- The position will open opportunities for careers in basic or applied research in academia and in the private sector.
Application
The application should include:
- a cover letter, with summary of motivation and research interests;
- a full curriculum vitae including a commented description of past activities; names and full contact information of at least one reference person.
- Please also indicate if you are currently authorized to work in Switzerland (and the type of visa, if available).
Please submit applications by e-mail with Subject line: “BCF-JobAd-Sept2014-PHDimm” to the address below. Please note that the mail might be processed automatically and the body of the mail might be disregarded. Please submit all files in pdf format attached to the mail as a compressed / zipped directory named “BCF-JobAd-Sept2014-PHDimm-YourFamilyName”. Thank you.
Job contact person Dr. Mauro Delorenzi Group leader BCF - Bioinformatics Core Facility
SIB Swiss Institute of Bioinformatics &
Ludwig Center for Cancer Research (University Lausanne)
E-mail: [email protected] http://www.isb-sib.ch/
Dr. Mauro Delorenzi
Head Bioinformatics Core Facility (BCF)
NCCR molecular oncology program at ISREC
E-mail: [email protected]
Phone: +41-21 692 4097 & +41-21 692 5857
NCCR molecular oncology program at ISREC
E-mail: [email protected]
Phone: +41-21 692 4097 & +41-21 692 5857
| Address 1 | Address 2 |
| c/o Swiss Institute Bioinformatics (SIB) Quartier Sorge, Btiment Gnopode, Office Room 2021 CH-1015 Lausanne, Switzerland Phone: (group) +41-21 692 40(91-98) Fax: +41-21 692 4055 Directions: Local Map and Ways | SREC (Swiss Institute of Experimental Cancer Research) Boveresses 155, Office Room D208 CH-1006 Epalinges, Switzerland Phone: (group) +41-21 692 5857 (secretary: Anne-Marie Rodel) +41-21 692 5939 Fax: +41-21 652 6933 Directions: Local Map and Ways |