Powerful modern technologies, including next-generation sequencing (NGS) and mass spectroscopy (MS), allow for rapid developments in systems biology and synthetic biology. These advances allow for an unprecedented approach for genomics, transcriptomics, epigenomics and proteomics, providing deeper insights into the interactions of genes, proteins and small molecules. Understanding how interacting biological systems regulate functional networks, chromatin, gene expression, signaling pathways and crucial cellular processes is essential for the future of systems medicine [1–8]. Although these innovative developments are considered pragmatic and funded by governments and industry, here the author discusses the latest advances and challenges in ‘rewiring’ cellular signaling circuits, and redesigning and editing genetic code for a systems medicine-based pragmatic revolution in health.
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Expert Review of Anticancer Therapy (ISSN 1473-7140) Expert Review of Anti-infective Therapy (ISSN 1478-7210) Expert Review of Cardiovascular Therapy (ISSN 1477-9072) Expert Review of Clinical Immunology (ISSN 1744-666X) Expert Review of Clinical Pharmacology (ISSN 1751-2433) Expert Review of Dermatology (ISSN 1746-9872) Expert Review of Endocrinology and Metabolism (ISSN 1744-6651) Expert Review of Gastroenterology and Hepatology (ISSN 1747-4124) Expert Review of Hematology (ISSN 1747-4086) Expert Review of Medical Devices (ISSN 1743-4440) Expert Review of Molecular Diagnostics (ISSN 1473-7159) Expert Review of Neurotherapeutics (ISSN 1473-7175) Expert Review of Obstetrics & Gynecology (ISSN 1747-4108) Expert Review of Ophthalmology (ISSN 1746-9899) Expert Review of Pharmacoeconomics & Outcomes Research (ISSN 1473-7167) Expert Review of Proteomics (ISSN 1478-9450) Expert Review of Respiratory Medicine (ISSN 1747-6348)
Expert Review of Vaccines (ISSN 1476-0584)
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