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Friday, 30 January 2015

PhD @ University of Turku

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A highly motivated PhD student who is enthusiastic about working in an inter-disciplinary environment. The studentship is a part of a research consortium that aims at integrating evolutionary genetics, ecological modelling and environmental sociology to understand the external drivers of life history changes in a heavily fished Atlantic salmon population complex and to advance sustainable use of these aquatic natural resources. This project has been recently funded as a part of the Finnish Academy Arctic Research program.

University of Turku - the campus that never sleeps

  • The Teno River, located in northernmost Europe, supports one of the largest and most biodiverse naturally reproducing stocks of Atlantic salmon in the world. The Teno salmon monitoring programme, that has been running for 40+ years and involves close co-operation between scientific research and local fishers, provides multiple sources of data for this project. In addition to long-term catch data, it includes an archive of over 100,000 scale samples, containing information on, for example, life history strategies and growth rates of the Teno salmon across four decades. These samples also provide a source of DNA for genetic monitoring and linking genotype and phenotype.

Statistical inference in the project will focus on several particularly intensively monitored populations within the Teno population complex, and aim at broadening the understanding of the overall population dynamics of Teno salmon. Genomic research will focus on understanding the genetic basis of life history traits studied in the ecological modelling component e.g. age-at-maturity and repeat spawning.

  • The PhD student is expected to contribute both to the genomic and ecological data analyses, and therefore enthusiasm for, and experience with, population genetics and/or ecological modelling is desired. A strong background in mathematics, (Bayesian) statistics, bioinformatics or genomics is an advantage. Depending on the interests of the student, there are possibilities to work in the genetics lab and/or participate in fieldwork on the Teno River.
  • Informal inquires and applications (as a single pdf file) should be addressed to Prof. Craig Primmer (craig.primmer@utu.fi). Applications should include a CV (with names and contact details of at least two referees), and a max. 2 page letter of motivation. Undergraduate students who are yet to graduate should also include a letter from a faculty member indicating an estimated graduation date.
  • Review of applications will commence on Feb 28 with the preferred starting date being June 2015. The position is available until (and therefore expected graduation date is) the end of 2018. The starting salary is 2171 EUR per month.
  • The supervisors of the project are Craig Primmer, University of Turku (http://users.utu.fi/primmer/), Jaakko Erkinaro and Henni Pulkkinen, Natural Resources Institute Finland (www.luke.fi). The student can be based at either of the supervisors’ departments in Turku or Oulu, but will be required to spend extended periods in both locations.

Monday, 26 January 2015

Most Recent Articles & Updates in Bioinformatics

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  1. Careers in Bioinformatics

  2. UCSF Taps Atul Butte to Lead Big Data Center

  3. Digital World Biology - Highlights from 2014

  4. Bioinformatics Core announce their training courses for 2015

  5. 11 Python Libraries You Might Not Know

  6. WuXi buys NextCode Health for $65M

  7. Bioinformatics: The Next Frontier of Metabolomics

  8. what makes for a good bioinformatics 'brand' name?

  9. BioInformatics Rolls Out Interactive Data Tools

  10. Workshops (2015)

  11. Dedicated Computing Goes Cluster Ready for Bioinformatics

  12. UCLA Research Center to Focus on Healthcare Big Data Analytics

  13. Genetics as a Social Network – A Data Scientist Perspective

  14. Bioinformatics Distro Bio-Linux 8.0.5 Now Available for Download

  15. More Rotavirus Vaccination Means Less Rotavirus

  16. New Tick-Borne 'Bourbon Virus'

  17. The 4C Genome Browser

  18. The Impact of Spatial Structure on Viral Genomic Diversity

  19. Journal of Proteomics & Bioinformatics

  20. Epilepsy Research Benefits from the Crowd

  21. Bioinformatics firm Eagle adds to senior team

Careers in Bioinformatics

Precision medicine integrates molecular and clinical research with patient data and outcomes, aiming to place the patient at the center of all elements. In this emerging field, bioinformatics is a core technology. Learn how bioinformatics has evolved to deal with Next Gen Sequencing data and explore new career opportunities for biomedical and clinical researchers

UCSF Taps Atul Butte to Lead Big Data Center

UC San Francisco has recruited a world-renowned expert in medical technology, Atul Butte, MD, PhD, to lead the new UCSF Institute for Computational Health Sciences, which will serve as a cornerstone of the university’s efforts to harness the power of “big data,” to lead to faster and more effective cures for patients worldwide.
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  • A noted expert in pediatrics and medical informatics at Stanford University, Butte brings the rare combination of deep knowledge in medicine and biomedical research, and technological fluency to lead in the new realm of computational health. The appointment will be effective April 1.

Digital World Biology - Highlights from 2014

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Bioinformatics Core announce their training courses for 2015

The Genome Center’s Bioinformatics Core facility has recently announced three training courses for 2015. Click on the links below for more details about the content of each course and for information on how to register:

11 Python Libraries You Might Not Know

There are tons of Python packages out there. So many that no one man or woman could possibly catch them all. PyPi alone has over 47,000 packages listed!

WuXi buys NextCode Health for $65M

China based WuXi PharmaTech has acquired NextCODE Health, a genomic analysis and bioinformatics company with operations in the United States and Iceland, for $65 million in cash.
  • WuXi plans to merge NextCODE Health and WuXi's Genome Center into a new company to be named WuXi NextCODE Genomics. The business will be headquartered in Shanghai, with operations in Cambridge, Massachusetts, and Reykjavik, Iceland. The leadership of WuXi NextCODE Genomics will include Dr Ge Li as CEO, Edward Hu as CFO, Hannes Smarason as COO, Dr Jeffrey Gulcher as CSO, Dr Hongye Sun as CTO, and Dr Hakon Gudbjartsson as VP Informatics.

Bioinformatics: The Next Frontier of Metabolomics

what makes for a good bioinformatics 'brand' name?

BioInformatics Rolls Out Interactive Data Tools

Life science industry research and advisory firm BioInformatics has launched a cloud-based analytics tool called Interactive Market Intelligence, through which end users can filter, create and export views of data.
  • BioInformatics and its SDi analytical equipment research division have access to an expert network of more than 72,000 life scientists through which to glean insights for clients. The firm also offers services to assess the size and attractiveness of scientific markets, optimize product configurations and pricing, validate corporate acquisitions, measure customer loyalty, and evaluate brand strength and positioning.

Workshops (2015)

Dedicated Computing Goes Cluster Ready for Bioinformatics

This week Dedicated Computing announced its participation in the Intel Cluster Ready program to deliver integrated HPC cluster solutions to the Life Sciences market. Powered by Intel Xeon processors, Dedicated Computing is offering a family of purpose built analytics and storage clusters for use in bioinformatics research.
  • Dedicated Computing’s HPC cluster, built upon Intel Cluster Ready architecture, will provide a fully integrated and optimized cluster. From entry level, compact clusters, featuring four multi-core homogeneous nodes, to those with hundreds of heterogeneous computing nodes, and combined with 20 Terabytes to multiple Petabytes of object store, these scalable solutions will be able to support the massive amounts of data that needs to be analyzed, interpreted and stored. These integrated cluster solutions contain securely maintained open source software stacks and cluster management that are designed to accelerate time-to-market, minimize costly validation and verification and enable 24x7x365 system monitoring for increased uptime.

UCLA Research Center to Focus on Healthcare Big Data Analytics

Researchers and faculty at UCLA will be diving into big data analytics at the newly formed Institute for Quantitative and Computational Biosciences (QCBio), a multi-disciplinary collaboration that hopes to foster personalized medicine.  Headed by Alexander Hoffmann, a professor of genetics, immunology, and microbiology, the Institute will attempt to answer pressing questions about the impact of genetics and other biological factors on the development and treatment of cancer, infectious disease, and additional conditions.
  • “UCLA’s Institute for Quantitative and Computational Biosciences will have a major, positive impact on human health,” said UCLA Chancellor Gene Block. “It will engage exceptional faculty from the life sciences and physical sciences, and our David Geffen School of Medicine and Henry Samueli School of Engineering and Applied Science to ensure that UCLA is at the forefront of research that will help usher in a new era of personalized health care, and to transform research and education in the biosciences.”

Genetics as a Social Network – A Data Scientist Perspective

Data science and biology have never really mixed well. And in retrospect, it’s pretty understandable why. Biology and medicine have their own lingua franca, which makes for a pretty steep learning curve. People who thrive at this intersection not only have to be in tune with the fundamentals of biochemistry and genetics, but also need to be mathematically adept and strong algorithmic thinkers.
  • For decades, we’ve gotten away with computer scientists sticking with computers and biologists sticking with genetics. But things are rapidly changing, and there’s a growing need for people who can bring a data-driven approach to medicine. The advent of modern high-throughput biotechnology has brought upon a data deluge that has completely changed the field’s landscape. For example, a binary alignment file for a single human genome could easily amount to hundreds of gigabytes or terabytes of raw data. Without data science, we risk missing out on valuable insights that could fundamentally change how we deliver medicine.

Bioinformatics Distro Bio-Linux 8.0.5 Now Available for Download

Bio-Linux, a fully-featured, powerful, configurable, and easy to maintain bioinformatics workstation built on the Ubuntu operating system, has been upgraded to version 8.0.5 and is now available for download. The Bio-Linux operating system is based on Ubuntu 14.04 LTS (Trusty Tahr), and the previous version was using Ubuntu 12.04 LTS.
  • Bio-Linux, a fully-featured, powerful, configurable, and easy to maintain bioinformatics workstation built on the Ubuntu operating system, has been upgraded to version 8.0.5 and is now available for download.

More Rotavirus Vaccination Means Less Rotavirus

The more children who are vaccinated againstrotavirus at your pediatrician’s office, the less likely it is that your child will be exposed to the gastrointestinal illness, a new studyhas concluded. That might sound like a no-brainer, but with vaccine coverage as low as 0%* at some practices included in this study, these findings have significant implications for children unable to be vaccinated against rotavirus.
  • Kids were more than three times more likely to have rotavirus if they were patients at a location where less than 40% of other patients received at least one dose of the rotavirus vaccine (compared to locations with at least 80% coverage).
  • Read More

New Tick-Borne 'Bourbon Virus'

Researchers have identified the cause of a Kansas farmer's mysterious death this summer as Bourbon virus.
Thought to be transmitted by ticks, the virus "was fast-moving and severe, causing lung and kidney failure, and shock," The New York Times reported, killing the previously healthy man after only 10 days in the hospital.
  • Bourbon virus, named after Bourbon County, Kansas, where the only known patient lived, is similar to viruses seen previously in Eastern Europe, Africa and Asia, said Hawkinson, but nothing like it had ever been identified in the Western Hemisphere before.

The 4C Genome Browser

The 4C Genome Browser serves more than 300 data tracks (100+ viewpoints at 2 to 4 experimental conditions). Due to the nature of 4C data, only a subset of 4C tracks are relevant to display given a particular genomic position. To improve your browsing experience, the browser is shipped with an internally developed JBrowse plugin named Dynamix.
  • It provides a complete dynamic browsing experience. A basic how-to is described below, focusing on introducing the different plugin elements and how to tweak and control Dynamix behavior.

The Impact of Spatial Structure on Viral Genomic Diversity

Most clinical and natural microbial communities live and evolve in spatially structured environments. When changes in environmental conditions trigger evolutionary responses, spatial structure can impact the types of adaptive response and the extent to which they spread.
  • In particular, localized competition in a spatial landscape can lead to the emergence of a larger number of different adaptive trajectories than would be found in well-mixed populations. Our goal was to determine how two levels of spatial structure affect genomic diversity in a population and how this diversity is manifested spatially.

Journal of Proteomics & Bioinformatics

Epilepsy Research Benefits from the Crowd

For millions of people with epilepsy, life comes with too many restrictions. If they just had a reliable way to predict when their next seizure will come, they could have a chance at leading more independent and productive lives.
  • That’s why it is so encouraging to hear that researchers have developed a new algorithm that can predict the onset of a seizure correctly 82 percent of the time. Until recently, the best algorithm was hardly better than flipping a coin, leading some to speculate that seizures are random neurological events that can’t be predicted at all. But the latest leap forward shows that seizures certainly can be predicted, and our research efforts are headed in the right direction to make them even more predictable. The other big news is how this new algorithm was developed: it’s the product of a crowdsourcing competition.

Bioinformatics firm Eagle adds to senior team

Eagle has appointed Michael Reynolds as vice president of global sales as it prepares to launch a new bioinformatics software platform that will allow 'intelligent sharing' of genomic data later this year.
  • Reynolds joins the Cambridge, UK-based company from Pilgrim Software, where he was director of EMEA sales, and during a 20-year pharma and life sciences career his prior roles include stints at Smart Analyst, APC Pharma and Etrials.

Saturday, 24 January 2015

Bioinformatics Analyst I @ Dana-Farber Cancer Institute

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Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

Working at Dana-Farber | Dana-Farber Cancer Institute

Overview

  • The Dana-Farber Cancer Institute seeks an Bioinformatics Analyst to perform analysis of new datasets generated in the context of clinically oriented cancer sequencing projects that advance efforts for precision (or “personalized”) cancer medicine.  The successful candidate will develop and support data processing and analysis tools, maintain datasets and databases, integrate tools and databases into existing high-throughput pipelines, and facilitate the display and the distribution of processed data.

These projects may include:

  • Prospective clinical sequencing to guide the care of cancer patients
  • Studies of resistance to targeted therapies and extraordinary responses
  • Studies of patient samples for tumor behavior and clinical outcomes
These projects involve collaborative efforts between Boston Children’s Hospital, the Dana-Farber Cancer Institute, and the Broad Institute.  The goals of these initiatives consist of analyzing sequencing data to determine the effects of genomic alterations and expression changes on clinical behavior, both retrospectively and prospectively.  The new data that emerge from these efforts could help identify novel approaches for genomics-driven care in oncology.  In addition, this data may provide support for new methods in clinical decision-making, biomarkers for rational drug development, and new insights into tumor biology through innovative analyses.
  • The analyst will join a dynamic and multidisciplinary team of clinical and translational investigators. He/she will participate in the design and implementation of algorithms to analyze the data and integrate with other data sets including clinical outcomes data; work with faculty and staff computational biologists to develop the tools needed for manipulating and preparing data for display; coordinate the transfer of raw and analyzed data to external collaborators and data repositories; and help maintain, support, and document shared tools, code base, and data sets. As the software infrastructure evolves, this position will present diverse and flexible opportunities - from deeper and more complex software design problems, to becoming more involved in the bioinformatics and analytical aspects of predictive modeling.
  • Requirements:  A B.S. or M.S. in bioinformatics, mathematical, physical, or computer science, or comparable research experience, together with significant experience in computer programming and computational biological applications. A strong background in statistics and biology is preferred. Experience managing and curating large datasets and with machine learning techniques is desired. Excellent oral and written communication skills and the ability to perform both self-directed and guided research are essential. The candidate must demonstrate outstanding personal initiative and the ability to work effectively as part of a team. Ability to meet deadlines and efficiently multitask is a must.The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases.

How to Apply

Read More/Apply

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PhD Student in Bioinformatics @ Luxembourg Institute of Health

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Project summary:
GPCRs heterodimerization appears to play a role in modulating agonist/antagonist affinity, efficacy and/or trafficking properties, the molecular models of GPCRs required to understand receptor function must consider these oligomerization hypotheses. To advance knowledge in this field, we would like to investigate the role of heterodimer GPCRs receptor inside the lipid-bilayer and also we would like to study GPCRs-ligand interactions through computational approach. Thereby we would like to explore the pharmaceutical potential of GPCR heterodimers for therapeutic intervention in HIV1 infection and in Cancer.

Detailed Description

  • Prepare a first draft with an in-depth analysis of the materials needed to complete the PhD subject
  • Carry out his/her PhD in accordance with the conditions agreed between the university and the laboratory (e.g. PhD charter defining the work relationship between the student and the supervisor)
  • Work with a researcher who has set up a research project and participate in the drafting of scientific articles about the ongoing project
  • Develop a scientific methodology and techniques adapted to the research project
  • Present the work as well as results during laboratory meetings and at international scientific meetings
  • Communicate problems and suggestions for possible solutions in a clear way
  • Publish in peer-reviewed international journals

Main professional relations:

  • Functional reporting line: project leader or researcher
  • Internal: project leader, members of the project team
  • External: dealing with external professional contacts as defined in his/her research projects

Job Requirements

Obligations:

  • The candidate will apply for a PhD at the Luxembourg Institute of Health with an AFR grant (research training aid from the Fonds National de la Recherche, Luxembourg) and will start his/her fixed-term employment contract for 3 years after acceptation of the grant by the FNR
  • Strictly follow the organizational procedures set up by the CRP-Santé
  • Respect the confidentiality of the data
  • Adapt working hours to project requirements

Specificity:

  • The PhD student must receive an AFR (research training aid) to complete his/her PhD
  • The candidate may be a student (for the whole PhD cycle)
  • Possibilities to travel abroad to learn new techniques

Additional Details

  • Master degree (or equivalent) in Bioinformatics or system biology or related disciplines
  • Experience in MD simulation, Molecular docking or molecular modelling related to G protein-coupled receptors is a plus
  • Knowledge in programming and Linux scripting are necessary
  • Rigor, motivation, scientific creativity and originality, writing skills, conciseness, sense of priority and sense of human relations
  • The candidate should be fluent in spoken and written English; preference will be given to applicants with good publication records in relevant areas

Complete your personnal information:

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Read More @ Luxembourg Institute of Health

Thursday, 22 January 2015

PhD @ Helmholtz Centre for Infection Research

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2015 is a special year for the Helmholtz Centre for Infection Research (HZI) in Braunschweig:turning 50! In October 1965 the first laboratories took up work on the campus were the HZI is now located.
Since the beginnings a lot has changed. Founded as the Institute of Molecular Biology, Biochemistry and Biophysics (IMB), the Federal Republic of Germany became the main stakeholder of the institute in 1975 which was then renamed as German Research Centre for Biotechnology mbH (GBF) in 1976. Since then the GBF was a member of the Association of National Research Centers (AGF), which later became the Helmholtz Association. From the early 2000s a shift in the research focus of the Centre started taking place resulting in the Centre being renamed Helmholtz Centre for Infection Research in 2006.

HZI International Graduate School

open vacancies @ Helmholtz Centre for Infection Research

  1. PhD Position in CRISPR-Cas9 biology and genome engineering

  2. PhD Position in infection biology and innate immunity

  3. PhD Position in Clp-mediated regulatory proteolysis in bacteria

PhD Position in CRISPR-Cas9 biology and genome engineering

Extended application period - The department Regulation in Infection Biology (Prof. Emmanuelle Charpentier) at the Helmholtz Centre for Infection Research in Braunschweig (Germany) is offering a PhD Position to investigate the biochemical mechanism of RNA-mediated CRISPR-Cas9 and further develop the system for targeted genome engineering in human cells. See recent key publications in 2011 (Nature 471:602-607), 2012 (Science 337:816-821) and 2014 (Science 346:1258096).

Area of research

  • The Helmholtz department “Regulation in Infection Biology” studies molecular and cellular mechanisms of regulation in processes of infection and immunity in Gram-positive bacterial pathogens. The group has recently focused on the RNA-programmable CRISPR-Cas9 endonuclease and is currently investigating the biochemistry of the system and its applications in genome editing and regenerative medicine. The project will be conducted in cooperation with the biotech company CRISPR Therapeutics.

Prerequisite

  • Master’s Degree/Diploma in Biology, Biochemistry, Bioinformatics, Biotechnology, Life Sciences, Microbiology, Immunology or related fields.
  • Former experience in molecular biology, biochemistry, genetics, cell biology and genome editing will be considered as an advantage.
  • Ability to work independently and as part of international and multidisciplinary consortia.
  • Ability to multi-task and to meet tight deadlines is essential.
  • Ability to work in a highly competitive field of research.
  • A strong desire to do research with high self-motivation and enthusiasm.
  • Excellent organization skills and personal initiative.
  • Excellent English communication skills (written and spoken).

Location

Research Group

The Handicapped

  • Qualified applicants with a disability will be given preference.

How To Apply

Applications accepted until 18.02.2015
The application period for this position has been extended. Please submit your application in online application tool at https://hzi.opencampus.net/ (after registration choose “Application HZI Jobs” and select job number 84/2014).
Within the online application, you have to provide a complete curriculum vitae including a list of publications and academic references, as well as a motivation letter outlining briefly your research experience, motivation in the position and own scientific interests within the context of the announced research topic. All documents and information should be provided in English.

PhD Position in infection biology and innate immunity

Extended application period - The department Regulation in Infection Biology (Prof. Emmanuelle Charpentier) at the Helmholtz Centre for Infection Research in Braunschweig (Germany) is offering a PhD Position to investigate mechanisms of interaction between Streptococcus pyogenes and the human host.

Area of research

  • The Helmholtz department “Regulation in Infection Biology” studies molecular and cellular mechanisms of regulation in processes of infection and immunity in Gram-positive bacterial pathogens. The group has recently focused on the mechanisms of interaction between Streptococcus pyogenes and innate immune cells. In this regard, the project will involve the investigation of mechanisms involved in the recognition of the bacterial pathogen by human host cells and will include the study of membrane vesicles in this respect. The position is announced within the frame of a recently funded European ERA-NET project, Infect-ERA Haplo-Infect.

Prerequisite

  • Master’s Degree/Diploma in Biology, Biochemistry, Bioinformatics, Biotechnology, Life Sciences, Microbiology, Immunology or related fields.
  • Former experience in immunology, molecular biology, biochemistry, bacteriology and genetics will be considered as an advantage.
  • Ability to work independently and as part of international and multidisciplinary consortia.
  • Ability to multi-task and to meet tight deadlines is essential.
  • Ability to work in a highly competitive field of research.
  • A strong desire to do research with high self-motivation and enthusiasm.
  • Excellent organization skills and personal initiative.
  • Excellent English communication skills (written and spoken).

Location

Research Group

The Handicapped

  • Qualified applicants with a disability will be given preference.

How To Apply

Applications accepted until 18.02.2015
The application period for this position has been extended. Please submit your application in online application tool at https://hzi.opencampus.net/ (after registration choose “Application HZI Jobs” and select job number 85/2014).
Within the online application, you have to provide a complete curriculum vitae including a list of publications and academic references, as well as a motivation letter outlining briefly your research experience, motivation in the position and own scientific interests within the context of the announced research topic. All documents and information should be provided in English.

PhD Position in Clp-mediated regulatory proteolysis in bacteria

Extended application period - The department Regulation in Infection Biology (Prof. Emmanuelle Charpentier) at the Helmholtz Centre for Infection Research in Braunschweig (Germany) is offering a PhD Position to investigate regulatory mechanisms of Clp-mediated protein quality control including proteolysis in Gram-positive bacterial pathogens.

Area of research

  • The Helmholtz department “Regulation in Infection Biology” studies molecular and cellular mechanisms of regulation in processes of infection and immunity in Gram-positive bacterial pathogens. The group has recently focused on mechanisms involving Clp-mediated protein quality control, toxin-antitoxins systems and RNAregulatory elements.

Prerequisite

  • Master’s Degree/Diploma in Biology, Biochemistry, Bioinformatics, Biotechnology, Life Sciences, Microbiology, Immunology or related fields.
  • Former experience in protein biochemistry, bacteriology, molecular biology and genetics will be considered as an advantage.
  • Ability to work independently and as part of international and multidisciplinary consortia.
  • Ability to multi-task and to meet tight deadlines is essential.
  • Ability to work in a highly competitive field of research.
  • A strong desire to do research with high self-motivation and enthusiasm.
  • Excellent organization skills and personal initiative.
  • Excellent English communication skills (written and spoken).

Location

Research Group

The Handicapped

  • Qualified applicants with a disability will be given preference.

How To Apply

Applications accepted until 18.02.2015
The application period for this position has been extended. Please submit your application in online application tool at https://hzi.opencampus.net/ (after registration choose “Application HZI Jobs” and select job number 86/2014).
Within the online application, you have to provide a complete curriculum vitae including a list of publications and academic references, as well as a motivation letter outlining briefly your research experience, motivation in the position and own scientific interests within the context of the announced research topic. All documents and information should be provided in English.

contact

  • You are encouraged to contact directly the Department Head. For questions regarding offered PhD projects, please contact Prof. Charpentier under: emmanuelle.charpentier@helmholtz-hzi.de.
  • The Helmholtz Centre for Infection Research (HZI) is a member of the Helmholtz Association of German Research Centres, the largest scientific organization in Germany. The HZI offers a unique research environment in the field of infectionbiology, excellent state-of-the-art equipment, a stimulating scientific community and intensive training of scientific and personal skills. Further information about the institute and the research department of Prof. Charpentier can be found on website: www.helmholtz-hzi.de.

Online Application of the HZI Graduate School

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Read More

http://www.helmholtz-hzi.de/en/career/jobs/phd_theses

Wednesday, 21 January 2015

Bioinformatics Jobs In INDIA

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  1. RAMALINGASWAMI RE-ENTRY FELLOWSHIP

  2. JUNIOR RESEARCH FELLOWS @ CSIR-CFTRI

  3. PROJECT ASSISTANT @ BHARATHIDASAN UNIVERSITY

  4. Senior Research Fellow @  NII

  5. Junior Research Fellow @ Bharathiar University

  6. SRF  @ Division Plant Pathology,IARI

  7. Senior Research Fellow @ NBFGR, Lucknow

  8. Studentship and Traineeship @ North-Eastern Hill University

  9. Project Assistant @ NATIONAL INSTITUTE OF NUTRITION

RAMALINGASWAMI RE-ENTRY FELLOWSHIP

Applications are solicited from Indian nationals working in overseas research institutions for the “Ramalingaswami Re-entry Fellowship” a re-entry scheme of the Department of Biotechnology (DBT), Ministry of Science & Technology, Government of India.

Aim of the Fellowship

  • The scheme is conceptualized with the aim of attracting highly skilled researchers (Indian nationals) working overseas in various cutting edge disciplines of biotechnology (agriculture,health sciences, bio-engineering, energy, environment, bioinformatics and other related areas),by providing them an attractive avenue to pursue their R&D interests in Indian institutions.

Who is eligible to apply ?

  • The applicant should possess a Ph.D., M.D., M. Tech, M.VSc. or equivalent degree with an outstanding track record as reflected in publications and other recognitions and with at least three years of post-doctoral research experience of which last two years should be from an overseas laboratory. Only candidates (Indian nationals) working overseas are eligible to apply.
  • Those who have already returned to India within one year of the closing date of this advertisement are also eligible.
  • Researcher’s upto 55 years of age as determined on closing date of application are eligible to apply.

Incentives of being a Ramalingaswami fellow

  • This is a senior fellowship programme, and awardees are to be considered synonymous to the faculty/scientists at the level of Scientist-D. They are entitled to take up teaching/research assignments and supervising Doctoral/MS students.
  • The scheme provides a consolidated monthly remuneration of Rs. 85,000/- p.m. In addition, a House Rent Allowance of Rs. 7,500/- p.m. is given to fellows. In case host institute provides accommodation to the fellow, no house rent allowance is admissible.
  • Fellows will receive a research/contingency grant of Rs. 10.00 lakhs for the 1st year; Rs. 7.50 lakhs for the 2nd year; Rs. 5.00 lakhs for subsequent 3 years for purchase of consumables, minor equipment, international and domestic travel, engaging manpower and other contingent expenditure to be incurred for the implementation of research proposal.
  • DBT encourages host institutions to provide medical benefits, transport allowance, leave travel allowance and other benefits as per their prevailing norms as applicable to their employees of the rank equivalent to Scientist D out of their own resources/ funds.

JUNIOR RESEARCH FELLOWS @ CSIR-CFTRI

Applications are invited from eligible candidates for recruitment of 2 [TWO] positions of Junior Research Fellows on a temporary contractual basis in the research project entitled "Probiotics for Antigen Delivery" (GAP-0438) funded by the Department of Biotechnology, Government of India, New Delhi tenable at the Department of Protein Chemistry & Technology (PC&T), CSIR-CFTRI, Mysore, Karnataka.
  • Essential Qualifications : First class postgraduate degree in science with specialization in Biological Sciences (Molecular Biology/ Biochemistry/ Microbiology/ Bioinformatics) with good academic records. Molecular Biology & animal handling experience candidates are preferred.
  • Emoluments : A Fellowship of Rs.16,000/- per month plus HRA as per DBT-CSIR Rules.

Terms & Conditions:

  1. Candidates should not have exceeded 28 years of age as on 31-01-2015 i.e., the last date of receipt of applications for the post.
  2. The engagement of JRF is exclusively for the above mentioned project.
  3. The engagement will be contractual and on purely temporary basis in the project funded by DBT, Govt. of India for a period from January, 2015 to August, 2016 and is co-terminus with the project, if the project terminates earlier.
  4. The engagement under the project does not confer any right/claim whatsoever either explicitly or implicitly on the appointee for regular appointment in CSIR/CFTRI, against any post or otherwise under any legal conditions precedent.
  5. No TA/DA will be given to the candidates for attending the interview.
Eligible candidates may send their complete Bio-data (Hardcopy) with e-mail address/contact phone number along with attested copies of the necessary certificates to Dr. K. Rajagopal, Principal Scientist, PC&T Dept. CSIR-CFTRI, Mysore – 570 020 on or before 31-01-2015.
  • Details of the research of Dr. K. Rajagopal may be seen at www.cftri.com/viewprofile.php?empno=2314.
    Applications received after the due date (i.e., 31-01-2015) will be rejected. The names of the short-listed candidates will be announced & displayed in CFTRI website.

PROJECT ASSISTANT @ BHARATHIDASAN UNIVERSITY

Project title: “Genome-scale metabolic modeling and simulation of rumen methanogens- An in silico attempt to methane attenuation”
  • Funding Agency: University Grants Commission, New Delhi
  • Tenure of the project: Two years or till the end of the project period.
  • Position: Project Assistant (1 no.)
  • Essential qualification: First class M.Sc. in Bioinformatics/Microbiology/Biotechnology and other related decipline.
  • Desirable qualification: Experience in an area relevant (Molecular Systems Engineering) to the project.
  • Fellowship: Rs. 5000 per month as per the UGC norms.
  • Upper age limit: 28 years
  • Date of Venue of interview: 22.01.2015, Department of Bioinformatics, School of Life Sciences, Bharathidasan University, Tiruchirappalli -620 024, Tamil Nadu
  • The above post is purely temporary and will be terminated with three month notice.
The Terms and the condition of the appointment shall be governed according to UGC, Govt.of India. The eligible candidates will bring their original certificates and documents at the time of interview. No TA/DA will be paid for attending the interview.

WALK-IN-INTERVIEW FOR PROJECT ASSISTANT

Senior Research Fellow @  NII

Applications are invited for the position of Senior Research Fellow & Attendant for the following time-bound sponsored project as per the details given below:
Name of the project & Duration of the Project Post details and
No of Posts
Name of the Project
Investigator Email ID
“Identification of novel DNA replication targets of UV irradiation” funded by DRDO
Tenable till – 30.07.2017
Senior Research
Fellow (P) (One Position
only)
Dr. Sandeep Saxena
Staff Scientist-V
saxena_lab@nii.ac.in

Qualifications:

  • Senior Research Fellow: M.Sc with 2 years of research experience in Life Sciences/Biotechnology/Biochemistry of any other related field.
  • Emoluments: The selected candidates will draw consolidated emoluments as per Institute Rules, depending upon qualifications & experience
  • Rs. 18,000/- per month consolidated plus 30% HRA ifqualified leading to Ph.D/NET/GATE otherwise Rs. 14,000/- per month plus 30% HRA.
  • Candidate should have experience in cell culture, protein purification and bioinformatics.

Junior Research Fellow @ Bharathiar University

Post: Junior Research Fellow
No. of Post: One
Duration: 3 Years
Title: DNA Barcoding to study the honey biodiversity in Mizoram
  • Emoluments: JRF @ Rs. 16, 000/- + 20% (Rs. 3,200/-) HRA for the first two years, SRF @ Rs. 18, 000/- + 20% (Rs. 3,600/-) HRA for third year (As per DBT norms)
  • Essential qualification: Candidate with Masters / M.Phil. in Biotechnology or in Life Sciences with Biotechnology as a subject.
  • Desirable qualifications: Experience in Molecular techniques and Bioinformatics.
  • Interview Schedule: Department of Biotechnology on 27.01.2015 at 9.30 AM
The interested candidates are requested to bring hard copies of their detailed CV along with experience and a note mentioning suitability of your candidature to the advertised position.Also bring a copy of attested certificates from matriculation onwards with all supporting original documents on 27.01.2015. The candidates are requested to strictly report between 9.00-10.00AM in Department of Biotechnology office for attending the Interview.

SRF  @ Division Plant Pathology,IARI

Walk-in-interview will be held in the Division of Plant Pathology, Indian Agricultural Research Institute, New Delhi 110012 to recruit one SRF under outreach project entitled ‘Diagnosis and management Strategies for virus and virus like diseases of crops’ .The eligible candidates may appear for the walk-in-interview on 25 th February 2015 at 10:00am along with their complete bio-data. Candidates should send their CV to email vkbaranwal@iari.res.in two weeks in advance
Name of Post No. of Post Emoluments
(Fixed) PM
Essential Qualifications Desirable
SRF One Rs 16000/-plus 30%HRA M.Sc in Biotechnology/Virology One year experience in
bioinformatics
, molecular
techniques and microarray
application

Application format

  • Name of the candidate, fathers name, date of birth, present and permanent address, Gen/OBC/SC/ST , qualification details with percentage marks from matriculation, research experience, self declaration regarding truthfulness in application, signature with date.

Senior Research Fellow @ NBFGR, Lucknow

Walk-in interview will be held on 28th January, 2015 at 10:00 hrs at National Bureau of Fish Genetic Resources, Lucknow (NBFGR) for the following positions on contractual basis under NFDB/NSPAAD funded project for "National Surveillance Programme for Aquatic Animal Diseases". Eligible and desirous candidate fulfilling all the requirements should come for an interview with duly filled in application giving full details of academic records and experience(s) along with attested photocopy as well as original copy of the relevant documents and a recent passport size photograph on the attached proforma. The details are as follows:
Name of
the Post
Post Duration of the
project
Emoluments Age limit Qualification and experience
Senior
Research
Fellow
Two upto 31st March,
2018 or coterminus
with the
project
`16,000/- +
20% HRA for
the first 2 years
and `18,000/- +
20% HRA for
the subsequent
year
35 years for men
and 40 years for
women as on date
of Interview.
Essential:Post graduation in
Computer Science/Computer
Application/Bioinformatics.
Desirable:Experience in database
management.

Studentship and Traineeship @ North-Eastern Hill University

  • Applications are invited for the Post of Research Associate, Traineeship and Studentship in the DBT sponsored Bioinformatics Infrastructure Facility (BIF) at the Bioinformatics Centre, Department of RDAP, North-Eastern Hill University, Tura Campus, Tura-794002, Meghalaya. The Posts are purely temporary and terminable at any time without prior notice or assigning any reason thereof. The person engaged, shall not be entitled for any claim implicit or explicit for permanent absorption in the University.

Project Assistant @ NATIONAL INSTITUTE OF NUTRITION

Eligible candidates are invited to attend WALK-IN-INTERVIEW on the following date at 9.30 A.M. sharp for filling up of the following position/post on the ad hoc research project entitled “Prevalence of deficiency of vitamin B12 and folic acid and hyperhomocysteinemia among urban geriatric population: A Population based cross-sectional study – funded by DBT” at this Institute. The essential qualification, experience, consolidated pay and service tenure are as under:
  • Essential Qualifications :1st Class M. Sc. (Biochemistry/Nutrition/Life Sciences).
  • Desirable : Research Experience in the analysis of Nutrients (Vitamins and Minerals) and metabolites. Knowledge and experience with soft wares related to bioinformatics are highly desirable.
  • Age : Not exceeding 28 years. Relaxation of age is admissible for SC/ST/OBC/PH Candidates as per the G.O.I. Rules)
  • Consolidated Pay : Rs.8,000/- p.m. fixed without any allowances.
  • Tenure : Initially for one year, extendable based on the performance.

Sunday, 18 January 2015

Bioinformatics Research Associate @ The University of Manchester

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Bioinformatics Research Associate
You will work within two laboratories that are part of an internationally recognised, high quality, multidisciplinary program that investigates several diverse aspects of eukaryotic gene expression. A number of projects in labs will be supported which use the latest genomics technologies, including ChIP-seq and RNA-seq, to study how cellular signaling affects transcription factor function and chromatin structure on a genome-wide scale. Both embryonic stem cells and mammalian embryogenesis are being studied (for recent publications see; Nucleic Acids Res. 40:3990-4001 doi: 10.1093/nar/gkr1240; Cell Reports, doi: 10.1016/j.celrep.2014.05.037). You will join two highly motivated research groups working on the molecular mechanisms of eukaryotic transcription factor function in the context of differentiation and development.

The University of Manchester - in our own words

Closing date : 11/02/2015
Reference : LSX-05845
Faculty / Organisational unit : Life Sciences
School / Directorate : School of Life Sciences
Division : Cellular Systems
Employment type : Fixed Term
Duration : 36 months
Location : Oxford Road, Manchester
Salary : £30,434 to £37,394 per annum
Hours per week : Full time
  • You should ideally possess (or shortly expect to gain) a PhD and have postgraduate qualifications and experience in bioinformatics analysis, including UNIX programming and database management. A desire to work on cutting edge aspects of gene regulation is essential.
  • The School of Cellular Systems is committed to promoting equality and diversity, including the Athena SWAN charter for promoting women’s careers in STEMM subjects (science, technology, engineering, mathematics and medicine) in higher education. The School received a Silver Award in 2009 for their commitment to the representation of women in the workplace and we particularly welcome applications from women for this post. Appointment will always be made on merit. For further information, please visit

Enquiries about the vacancy, shortlisting and interviews:

Professor Andy Sharrocks
Email: a.d.sharrocks@manchester.ac.uk or
Nicoletta Bobola
Email: Nicoletta.Bobola@manchester.ac.uk

General enquiries:

Email: hrservices@manchester.ac.uk
Tel: 0161 275 4499
Technical support:
Email: universityofmanchester@helpmeapply.co.uk
Tel: 01565 818 234
  • Date of external posting:13th January 2015
  • This vacancy will close for applications at midnight on the closing date.

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